Routine-friendly tablets for easy daily use
Large cohort metagenomic analyses of biopsy-proven NAFLD found that members of Ruminococcaceae are depleted as fibrosis advances in non-obese patients, and follow-up causal experiments showed that oral administration of a human-derived strain, Ruminococcus faecis , reduced serum ALT/AST, diminished collagen deposition and downregulated fibrogenic transcripts (Col1a1, Timp1, -SMA) in multiple mouse NAFLD models (MCD, CDAHFD and db/db), supporting a strain-specific hepatoprotective role (111, 112)
linagliptin suppressed elevated RAAS receptor expression with concomitant suppression of cardiac fibrosis and immune and inflammatory response [35]
Given that IBS symptoms can include diarrhoea, constipation, bloating, and pain, IBS patients are understandably concerned about how GLP-1 medications might influence their sensitive digestive systems