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However, this was not associated with a significant improvement in motor behavior[42], suggesting that targeting muscle alone without restoring motor neuron function is not sufficient to reverse a severe form of SMA

There is also a striking difference in the time for which both diseases have been present in the population and how long individuals have suffered from them

In summary, we found that high glucose increases ROS production in PSCs, which in turn activates PSCs by upregulating the TGF signalling pathway to promote their proliferation and migration

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