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Whether they are Solar Lentigines (induced by UV) or Lentigo Simplex (unrelated to sun), these lesions require targeted medical intervention to be successfully reversed

This entire process is highly dependent on cellular energy, requiring adenosine triphosphate (ATP) to function correctly

Its well-known adverse events, e.g., interstitial pulmonary fibrosis, seizures, liver veno-occlusive disease, or sinusoidal obstruction syndrome [96] seem to be caused by glutathionyl-tetrahydrothiophene, a metabolite that derives from the irreversible GSH conjugation [97,98]

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