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Zhang HJ, Chen J, Yang YL et al (2019) Discriminative detection of glutathione in cell lysates based on oxidase-like activity of magnetic nanoporous graphene

In this study, we demonstrate that AML cell death occurring early after APR-246 exposure is suppressed by iron chelators, lipophilic antioxidants and inhibitors of lipid peroxidation, and correlates with the accumulation of markers of lipid peroxidation, thus fulfilling the definition of ferroptosis, a recently described cell death process

In this model, genes associated with the one-carbon metabolic pathways, including the folate and methionine cycles, are up-regulated in the fungal cells upon infection, and are supposed to result in enhanced biosynthesis of nucleotides, NADPH, glutathione and methyl groups

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