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Treating individuals with obesity and impaired glucose metabolism with GLP-1 receptor agonists has already been reported to prevent the onset of diabetes, at least for a treatment period lasting 1 or 2 years [17]

She emphasizes the importance of patient education and thorough screening to identify individuals at higher risk for these side effects

Regarding the underlying mechanism, IR in the brain significantly contributes to neurodegenerative processes, and GLP-1RAs modulate downstream signaling pathways, including mitochondrial biogenesis, autophagy, inflammation, and cell survival

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