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In a Phase II readout released in August 2022, the pharma touted a 15.6% drop in body weight in patients taking CagriSema, versus 5.1% in comparators on semaglutide alone and 8.1% in patients treated with only cagrilintide
The tradeoff is that more water means fewer total days per vial (you cannot exceed the 28-day reconstituted shelf life) and a higher volume per injection
16 Sometimes muscle twitches (hypnic jerks) occur during this sleep stage, which lasts only a few minutes, representing 25% of total sleep time
For weight management , NHS eligibility is more restrictive
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