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Amgen management on the call also described high-level results from a Phase 1 study evaluating a three-step dose escalation of the drug, according to a Friday note from William Blair

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While manufactured seals are factory tested to assure compliance with ISO and/or YBB flip-off force specifications as a matter of quality control, crimped and conditioned vials may need to be demonstrated to meet certain minimum flip-off force specifications to ensure that seal caps do not disengage during transportation and storage

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