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While proliferation of HCT116 cells was not affected by knocking down PGRMC1, PGRMC1-KD cells were more sensitive to the EGFR inhibitor erlotinib than control HCT116 cells, and the knockdown effect was reversed by co-expression of shRNA-resistant wild-type PGRMC1 but not of the Y113F mutant (Fig
Aussi, dautres tudes ont pu mettre en avant que l'augmentation du taux de glutathion permettait damliorer la sant cardio-vasculaire, car le pouvoir antioxydant du GSH protge les fibres musculaires cardiaques du stress oxydatif
Toronto, Canada: Cold Spring Harbor Laboratory (2018)
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