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However, based on the wide therapeutic index of metformin, the slightly greater exposure when coadministered with oral semaglutide was not considered to be clinically relevant

In recent years, the regulator has specifically highlighted risks associated with counterfeit and falsified versions of GLP-1 receptor agonists, including semaglutide, and has extended its vigilance to newer investigational compounds being marketed prematurely to consumers

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Lower prices don't always mean lower quality, but extremely low prices should prompt questions about sourcing and quality control