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In a 2-year study that set out to determine if targeted nutritional supplements improve visual acuity and visual function in AMD, patients treated with lutein (10mg) zeaxanthin (1mg) and astaxanthin (4mg) together with other nutrients reported significantly greater clinically meaningful stabilisation or improvement in symptoms compared with non-treated subjects

No improvement on the other hand would suggest that MTHFR may not be the dominant cause of fatigue even if MTHFR testing is positive

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Funding: This work was supported in part by the Ontario College of Pharmacists through funding in support of the Pharmacy5in5 program