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It presents with a broad clinical spectrum, ranging from asymptomatic or non-specific symptoms, such as fatigue or lightheadedness, to severe manifestations, including nausea, vomiting, alteration of consciousness, and even coma, which can be life-threatening 3,4

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collagen synthesis pathways

Some describe feeling: Warmth in the face or chest A brief increase in energy or alertness Mild tingling A temporary metallic taste Mild pressure or cramping sensation These sensations are usually short-lived and are thought to reflect the rapid cellular and metabolic activity triggered by NAD as it supports mitochondrial function and cellular energy production