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On 21 July 2017, the Philippine Tobacco Institute (PTI), a trade association of cigarette manufacturers in the Philippines filed a petition for prohibition against Balanga City on the grounds of pre-emption, alleging prohibitions delineated in the Comprehensive No-Smoking Ordinance - CNSO (prohibiting sales and use within a 3km radius of the city's university town) supersede and therefore violate national regulations established by the Tobacco Regulation Act of 2003

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Fertil Steril 83:10931099 Jana K, Samanta PK, De DK (2010) Nicotine diminishes testicular gametogenesis, steroidogenesis, and steroidogenic acute regulatory protein expression in adult albino rats: possible influence on pituitary gonadotropins and alteration of testicular antioxidant status