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Berberine can also be used in combination with other drugs such as levetiracetam and curcumin to enhance its neuroprotective effect by reducing inflammation and oxidative stress (Lin et al., 2020

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The peptide's four-residue structure makes it one of the smallest bioactive peptides studied in longevity research, and its compact size contributes to favorable pharmacokinetic properties including rapid absorption from subcutaneous injection sites