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NTFs are crucial for CNS development and play vital roles in neurogenesis, neuronal cell migration, and CNS cell survival [14]

Furthermore, semaglutide treatment resulted in a significantly higher percentage of patients with NASH resolution than placebo in the phase II trial involving patients with NASH [80]

278 Similarly, the enriched histone Kla, particularly H4K12la, is detected in vascular smooth muscle cells (VSMCs), activating senescence-associated secretory phenotype (SASP) transcription and exacerbating VSMC senescence

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