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The alternative total rebate amount is equal to the product of all of the following: (1) The AnMP for the applicable period, as calculated in 428.202(b), of the Part D rebatable drug that is a line extension of a Part D rebatable drug that is an oral solid dosage form

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For example, smokers with different baseline microbiome compositions may exhibit distinct responses to smoking

Smokeless Tobacco: The Statistics Smokeless tobacco consumption was widely prevalent in the 19 th century but after the invention of cigarettes, consumption of smokeless tobacco came down considerably