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The current paradigm to address non-pulmonary vein sources of AFib is to extend the ablation to include more atrial tissue, which has had limited success

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Neurology/Psychiatric July 12, 2023 Novartis AG has described pyridine-3-carboxylate compounds acting as voltage-dependent L-type calcium channel subunit -1C channel (Cav1.2) activators reported to be useful for the treatment of schizophrenia, major depression, attention deficit hyperactivity disorder, autism spectrum disorder, multiple sclerosis, frontotemporal dementia, Alzheimers disease and Brugada syndrome