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The findings illustrate a recurring observation in IGF-1 LR3 research: mass-level effects do not necessarily translate to functional recovery, and delivery kinetics appear to be a critical variable in study outcomes

Pair that with exhaustion (a common side effect) and reduced motivation to work out, and your body starts dipping into muscle as fuel, especially if you're not lifting or prioritizing strength

The dual action makes tirzepatide particularly effective at reducing appetite without relying entirely on GLP-1's side effects, while also improving lipid profiles and metabolic markers