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Study author Ludmil Alexandrov said in a statement that before now, we had a large body of epidemiological evidence linking smoking with cancer, but now we can actually observe and quantify the molecular changes in the DNA due to cigarette smoking. Co-author Sir Mike Stratton added that looking in the DNA of cancers can provide provocative new clues to how cancers develop and thus, potentially, how they can be prevented.

Taking a Stand: Artist David Bradley. Santa Fe New Mexican, September 23, 2016

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For instance, a higher nicotine concentration means you can absorb more nicotine in each puff