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Availability of data and materials The datasets analyzed during the current study are available in the IPUMS repository at Abbreviations NHIS: National health interview survey HR: Hazard ratio CI: Confidence interval IPUMS: Integrated public use microdata series NDI: National Death Index ICD: International classification of diseases and related health problems BMI: Body mass index CPS: Cancer prevention study TUS-CPS: Tobacco use supplement to the current population survey References Rostron BL, Corey CG, Gindi RM

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If you use both e-cigarettes and smoke cigarettes at the same time, you run the risk of developing a condition known as nicotine poisoning. Taking in too much nicotine at once can cause a variety of symptoms, including nausea, vomiting, dizziness, confusion, a racing heart, and even death

In contrast, other cells of the body suffered only indirect damage, as tobacco smoking seems to affect key mechanisms in these cells that in turn mutate DNA. Joint lead author of the study from the Wellcome Trust Sanger Institute says, Our research indicates that the way tobacco smoking causes cancer is more complex than we thought