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Over years, this increases the risk of cancer even in people who have never smoked. Unlike smoking, where risk depends on consumption, pollution exposure is uniform and unavoidable, making entire urban populations vulnerable

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Moreover, its impact on isoforms CYP1A2, CYP2A6, CYP2C8/9/10, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A4/5, and CYP4A has also been shown to be negligible in vitro