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doi:10.3133/ofr80973

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It has occasionally been used to treat Tourette syndrome, attention deficit hyperactivity disorder, and for severe pain management in some patients that is not relieved by standard pain medications

The paper, International randomised controlled trial evaluating metabolic syndrome in type 2 diabetic cigarette smokers following switching to combustion-free nicotine delivery systems: the DIASMOKE protocol, was originally published on April 1, 2021