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SAE, Gold Leaf Tobacco Corp., Golden Tobacco Ltd., Gudang Garam, Imperial Brands Plc, ITC Ltd., Japan Tobacco Inc., KT and G Corp., Modi Enterprises, Poschl Tabak GmbH and Co KG, PT Djarum, Pyxus International Inc, Scandinavian Tobacco Group AS, Swedish Match AB, Swisher International Inc., Universal Corp., Vector Group Ltd., and Vietnam National Tobacco Corp

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For example, in IL-1-deficient mice, neither local tumors nor lung metastases developed after localized or intravenous inoculation with melanoma cell lines, which suggests that IL-1-induced inflammation participates in the invasiveness of already existing tumor cells [65]