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39 This association may have arisen because the form of selenite used in supplements forms endogenous selenium nanoparticles, inhibits glycolysis, and leads to mitochondrial malfunction, autophagy, and cytoskeletal depolymerization

The quantity of food consumed may trigger gastrointestinal symptoms

41,48,50 Reactive oxygen species (ROS) (which are generally thought to be cytotoxic molecules) produced during metabolism have been shown to amplify insulin secretion

There are, however, clinical trials highlighting one of the possible glutathione side effects, which is that it may constrict the airways of people with asthma when it is inhaled via a nebulizer