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The world No 1 recovered from uncharacteristically slow starts at the WM Phoenix Open and AT&T Pebble Beach Pro-Am to finish inside the top-four in both, only to see his record-breaking run of 18 consecutive PGA Tour top-10s ended at the Genesis Invitational

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Specifically, when serum cotinine levels exceeded 487 ng/ml, testosterone levels began to decline

MLE to nicotine was obtained for each extract by using the measured human tip nicotine values and the linear regression equation obtained by plotting mainstream smoke nicotine yield versus tip nicotine data obtained during calibration