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PLoS One 18 , e0289616 (2023)
Meta-analyses further corroborate this effect: compared with SGLT2 inhibitors or statins, GLP-1RAs are associated with more pronounced changes in EAT, with stronger beneficial effects following long-term (over 6 months) administration
Either way it appears to have neuroprotective factors
In a systematic review of 55 double-blinded, placebo-controlled randomized clinical trials, GLP-1RA treatment was associated with an increased risk of cholelithiasis compared with placebo (RR 1.46, 95% CI 1.091.97) but not cholecystitis, cholangitis, or pancreatitis (63)
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