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Symptoms of chronic bronchitis may include: cough (called smokers cough) excessive mucus production coughing up mucus wheezing chest discomfort or tightness shortness of breath crackling sounds while breathing More severe effects that might appear as the condition worsens include: bluish lips, fingernails, and skin because of reduced oxygen levels swollen feet heart failure Treatment for chronic bronchitis aims to relieve symptoms, prevent complications, and slow the progression of the disease

The nicotine levels do pose an addiction risk for non-tobacco users who initiate use of these products

Variations in genes related to nicotine metabolism, receptor sensitivity, and reward processing increase the risk of developing dependence on tobacco products

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