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Direct pro-allergic effects of tobacco smoke through DCs First, tobacco smoke itself might contain the putative DC-targeted pro-allergic trigger

The evidence is sufficient to infer that exposure of nonsmokers to secondhand smoke causes a significant increase in urinary levels of metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

[2] [3] Although the Diablos originated in California, the club established its most significant presence in New England

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