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"Author Michael Pollan wrote about his horrifying experience of ego loss on 5-MeO-DMT, saying it felt like being strapped to the outside of a rocket." As for how it compares to other psychoactive substances, toad venom is in a class all its own, he says, and is widely agreed to be "the most powerful psychoactive drug on Earth." Safety and Risks of Toad Venom Use of all drugs carries certain risks, Dow explains, and toad venom is no different
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