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Ibuprofen should be used with caution if you have gastrointestinal problems, kidney disease, asthma, or are taking certain medications including anticoagulants

[PubMed] [Google Scholar] 143.Xiao J, Lv Y, Lin B, Tipoe GL, Youdim MB, Xing F, Liu Y

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Both the occluded and the inward-facing structures show Na + coordinated deep within an aqueous cavity that is allosteric to the carnitine-binding site