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Together, these factors create a formidable barrier to cessation, requiring significant effort and support for successful quitting

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Based on this information, we do not believe there is enough pricing data to support an increase in the price of the SL484 supply from $4.247 to $6.130, and we are not proposing an increase in the price of this supply

To our knowledge, this study is by far the most extensive and fully adjusted prospective study of lung cancer incidence treating smoking as a single modifiable factor and incorporating multiple genetic-risk factors