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"He had very serious respiratory failure, he had to go to ECMO and that is a very big deal," Dr Jayesh Bhatt, a consultant at Nottingham University Hospitals, told BBC News

No In-Flight Vaping or Charging: Using or charging your vape device or its batteries at any time while on the aircraft (including in lavatories) is illegal and strictly prohibited by all airlines

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Multivariate imputation by chained equations is a robust method for imputation and recommended above other methods such as mean imputation or complete case analysis which can bias results [38]