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[7] Use of chewing tobacco also seems to greatly raise the risk of non-fatal ischaemic heart disease among users in Asia, although not in Europe

Given the pervasive and multifaceted detrimental effects of tobacco on liver health, promoting and facilitating smoking cessation should be a cornerstone of clinical practice for all healthcare professionals, particularly hepatologists and gastroenterologists

This requires systematic screening, structured counseling, integration of pharmacologic therapies, and referral to specialized cessation services supported by a multidisciplinary approach

Patients themselves may also face considerable hurdles