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An important clue to this mystery may be found, I believe, in a comparison of the increase in the number of cigarettes being sold and the increase in the actual amount of tobacco being bought by the tobacco companies for use in cigarettes

The authors would like to acknowledge Tony Blakely, University of Melbourne, and Andrew Waa, University of Otago, for helpful comments and suggestions

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Weve now dated its use in our area 1,500 years earlier than the earliest dates we had. The discovery came from tests that found traces of nicotine in a pipe (or medicine tube) found decades ago at a now-submerged site along the Flint River in northern Alabama, a tributary of the Tennessee River