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The crucial role of the substantia nigra dopaminergic neurons in operant conditioning for food emerged from data showing that selective restoration of dopamine production in substantia nigra or its primary terminal target, the dorsal striatum, is sufficient to restore the motivation to work for food in mice that lack dopamine otherwise (Sotak et al., 2005

GIP receptor activation adds something different

Many patients begin to see weight loss results within the first few weeks of treatment, with more significant results typically occurring over several months

A topical numbing cream will be applied prior to the injection if requested