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The most frequent side effects, which tend to affect between 10% and 25% of people, include: Gastrointestinal problems like nausea, vomiting, stomach discomfort, diarrhea, and constipation Headaches Dry mouth Feelings of fatigue or physical weakness Dizziness Insomnia or an inability to sleep normally Drowsiness or tiredness Other side effects that have been found to impact up to 10% of people taking Zoloft include: Excess sweating Mood changes like restlessness, agitation, nervousness, or irritability Tremors Visual problems like blurred vision Fast heart rate It is important to recognize that not everyone will experience significant side effects

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