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Retatrutide may appeal more to people who have tried single-agonist GLP-1 medications without reaching their desired results, or those looking for a treatment with potentially greater weight loss outcomes

SOUL was a randomized, double blind, parallel-group, placebo-controlled superiority trial that enrolled 9,650 adults with T2DM who had established atherosclerotic cardiovascular disease (ASCVD), chronic kidney disease (CKD), or both, to receive a maximum daily dose of 14 mg oral semaglutide or placebo

(2014) provided further evidence that the serum acylcarnitines levels (Table 3) were influenced by antidote treatment in patients