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In addition, the increase in cannabis legalization and an evolving policy landscape concerning cannabis has rapidly brought about new products that should be monitored to ensure that these products do not attract new youth users

The correlation between e-cigarettes and an elevated risk of ACS has been verified in many studies

Do what you want to do, and follow your hearts desire

Constructed by: Tracy Gray Edited by: Will Shortz Todays Reveal Answer: One-Up Themed clues are all in the across-direction, and use the letters ONE written in the up-direction in the grid: 69A Outdo or a hint to entering four answers in this puzzle : ONE-UP 18A Strategy used in basketball and football : Z ONE DEFENSE 33A Exclamation of surprise : HOW ON E ARTH