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Selected Foreign Regulators Vary in Their Reliance on Alternative Tools to Oversee Drug Manufacturing All seven of the selected foreign regulators we interviewed varied in the extent to which they rely on alternative tools to substitute or supplement in-person inspections in other countries.[74] The capacity to conduct inspections and the use of alternative tools are affected by the level of resources available to each regulator, according to a report by the National Academies of Sciences, Engineering, and Medicine.[75] Member states of the European Union, like FDA, are among the most highly resourced regulators, and European Union officials reported that member states rely more heavily on conducting foreign inspections, while using alternative tools as a supplement

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Singed Nasal Hairs: Exposure to intense heat from smoke can cause singed nasal hairs

More frequent puffs overheat the cigar, creating harsh, bitter flavors