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A fairly recent addition to the tobacco market, sales of sub 12.5g pack sizes of RYO tobacco have more than doubled over the past year as increasing numbers of tobacco shoppers seek quality products with a low out of pocket spend

They created an estimated $864 million in total cost savings including $26,000 for every premature death avoided, $2,200 for every birthday saved, and $2,000 for every year of good health gained

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Increased oxidative stress due to smoking contributes to atherosclerosis by inducing cell proliferation, cell hypertrophy, and apoptosis, either directly through vascular endothelial damage or through activation of various intracellular signaling pathways