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Clinical data suggest it may also improve blood glucose levels, HbA1c, insulin sensitivity, blood pressure, and lipid-related markers , making it a broader metabolic therapy candidate rather than a weight-loss-only drug

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In humans, metabolically healthy obesity is associated with smaller adipocytes and a lower visceral-to-subcutaneous fat ratio, whereas expansion of visceral fat correlates with systemic insulin resistance and ectopic lipid deposition 46,47,48