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La libration de la cafine depuis les solides avec diffrent structure (MIL53, MIL88 et MILlOO), et dans les solides base de ligands modifis MIL53_2COOH, MIL53_2OH et MIL53_NH2 a t ralis par la suspension de 50mg de matriaux contenant la cafine dans 5mL d'une solution de tampon phosphate saline PBS (Aldrich) pH=7.4 a 37 0 C sous agitation.The release of caffeine from the solids with different structure (MIL53, MIL88 and MIL100), and in the solids based on modified ligands MIL53_2COOH, MIL53_2OH and MIL53_NH2 was achieved by the suspension of 50 mg of caffeine-containing materials in 5 mL of a solution of phosphate buffered saline PBS (Aldrich) pH = 7.4 at 37 C