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Key Ways Smoking Harms the Kidneys Narrows blood vessels, reducing kidney blood flow Increases blood pressure, a major risk factor for kidney disease Promotes inflammation and oxidative stress Accelerates decline in kidney filtration rate (eGFR) Increases protein leakage in urine (proteinuria) These effects gradually weaken kidney function and may lead to chronic kidney disease if smoking continues over time

Christman, a professor of medicine at Vanderbilt University who volunteers as a national spokesman for the American Lung Association

One in four patients in a hospital bed is a smoker

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