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8090% RPMI (1640) basic medium (Dalian Meilun Biotechnology Co., Ltd) + 1020% common fetal bovine serum (NEWZERUM) + 1% double antibody (penicillin/streptomycin) solution (Dalian Meilun Biotechnology Co., Ltd)

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HO-1 was involved in the protective effect of telmisartan against DN, and the mRNA levels regulation of Nrf2 and HO-1 indicated that telmisartan had a regulatory effect on apoptosis besides anti-inflammation and anti-oxidation [153]

Research indicates that nootropic peptides can stimulate the production of BDNF, a crucial growth factor that plays a vital role in neurogenesis and combating neurodegeneration