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Using a nicotine replacement product during pregnancy or while breast-feeding may be safer than smoking

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Nevertheless, the main components of cigarette smoking has inflammatory-regulatory properties, for instance, Heme oxygenase-1 (HO-1) and carbon monoxide (CO) play a role in modulating cytokine expression and macrophage bactericidal activity, regulating intestinal homeostasis and mucosal immune responses to the enteric microbiota [155, 156], both of which were involved in the possible pathological process in UC

Quitting smoking is one of the most impactful decisions you can make for your health