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Large meta-analyses involving over 4,000 stool samples from North America, Europe, and Asia show that PD is associated with a reproducible pattern of gut dysbiosis characterized by SCFA-producing genera depletion, opportunistic pathobiont enrichment, and consistent shifts in functional pathway gene expression [187]

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Safety Screening and Genetic Predispositions: Who Benefits Most from Which Option The PlexusDx Precision Peptide Genetic Test analyzes GLP1R (rs6923761), GIPR (rs1800437), FTO, and MC4R variants that relate to GLP-1 and related signaling pathways