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Testosterone, being an important androgen plays a pivotal role in several aspects of sexual maturation, behavior, spermatogenesis, differentiation, and maintenance of accessory sex organs.[13] The synthesis and release of androgens is dependent on the pituitary gonadotrophins, which are FSH and LH

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Among the isoenzymes, the induction of CYP1A2 is of clinical importance because many drugs are its substrates