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SLC3A1 has been indicated to promote the proliferation of stem cells in hepatocellular carcinoma cells (53) and was evidenced to be an effective therapeutic target in metastatic colorectal cancer through the recognition of metabolic signatures specific to metastatic cell lines (54)

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Paradoxically, EMFs exhibit context-dependent duality: low-intensity fields exacerbate malignancy by rewiring calcium/EVs-driven tumor-microenvironment interactions, while high-intensity fields achieve tumor ablation via calcium overload, ferroptosis, hyperthermia, or electroporation

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