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Consistent with nicotines anti-inflammatory effects, chronic nicotine administration via an osmotic minipump did not increase either TNF- or IL-1 in the nucleus accumbens in male mice (160), thereby supporting the notion that the constituents in the JUUL pods, or the interaction of nicotine with the constituents, led to the changes in inflammatory markers

doi: 10.1126/scitranslmed.3002042

From electrical accessories to dropped cigarettes to stored chemicals, the triggers are more numerous than most owners think

(Source) Of Americans who have been told by a healthcare provider that they have depression, 19.4% are smokers