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Canadian authors of a 2020 meta-analysis of 32 RCTs of drug treatment for major depressive disorder in people with concurrent SUDs concluded that SSRIs either alone or in combination with relapse prevention medications such as naltrexone, had no significant effect on depressive symptoms

That means the powerful oil magnate businessmen and Mexican drug cartel bosses he crosses paths with, as well as his vivacious, red-hot-crazy, and troublemaker wife, Angela (Ali Larter)

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