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Curr Hypert Rep (2005) 7:46673 10.1007/s11906-005-0043-y [DOI] [PubMed] [Google Scholar] 62.Khachaturian AS, Zandi PP, Lyketsos CG, Hayden KM, Skoog I, Norton MC, et al

This is because B12 is essential for producing myelin, a fatty substance that surrounds nerve fibers and helps them function properly

While there is no definitively established direct mechanism by which GLP-1 receptor agonists cause fatigue, several biological pathways warrant consideration